The Church of the Gesù (chiesa del Gesù), Church of Saint Mary of Gesu (chiesa di Santa Maria di Gesù) or Casa Professa is one of the most important Baroque churches in the Italian city of Palermo and in all of Sicily.
The Jesuits arrived in Palermo in 1549, and by the late 16th century began building a church adjacent to their mother house (Casa Professa) using a design by the Jesuit architect Giovanni Tristano. The original design called for a single nave with large transepts and several side chapels, but it was changed by the early 17th century, to a more grandiose layout typical of Jesuit architecture. Natale Masuccio removed the chapels' dividing walls to add two side naves to the central one. The church was consecrated in 1636.